Identification—
A:
Shake a portion of finely powdered Tablets, equivalent to about 5 mg of iodoquinol, with 10 mL of carbon disulfide, and filter: the filtrate responds to
Identification test
A under
Iodoquinol.
B:
Place a portion of the powdered Tablets prepared for the
Assay, equivalent to about 50 mg of iodoquinol, in a dry test tube, add 1 mL of sulfuric acid, and warm gently: violet vapors of iodine are evolved.
Soluble iodides—
Digest a quantity of powdered Tablets, equivalent to 100 mg of iodoquinol, with 5 mL of water for 10 minutes, cool, and filter. To the filtrate add 1 mL of 3 N hydrochloric acid, 2 drops of
ferric chloride TS, and 2 mL of chloroform, shake gently, and allow to separate: any violet color in the chloroform is not more intense than that in a blank to which 0.2 mg of potassium iodide has been added.
Assay—
Weigh and finely powder not less than 20 Tablets. Using a portion of the powder, accurately weighed and equivalent to about 14 mg of iodoquinol, proceed as directed in the
Assay under
Iodoquinol. Each mL of 0.02 N sodium thiosulfate is equivalent to 0.6616 mg of C
9H
5I
2NO.
701
:
1 hour.