(Official January 1, 2007)

Assay preparation— Weigh accurately not less fewer 10 Capsules in a tared weighing bottle. With a sharp blade, or by other appropriate means, carefully open the capsules, without loss of shell material, and transfer the combined capsule contents to a 100-mL beaker. Remove any adhering substance from the emptied capsules by washing with several small portions of n-hexane. Discard the washings, and allow the empty capsules to dry in a current of dry air until the odor of n-hexane is no longer perceptible. Weigh the empty capsules in the original tared weighing bottle, and calculate the average net weight per capsule. Transfer an accurately weighed portion of the combined capsule contents, equivalent to the quantity of Vitamin E specified for the Assay preparation in the Assay for the labeled form under Vitamin E, dissolve in and dilute with Internal standard solution to volume, and mix.