Packaging and storage—
Preserve in tight, light-resistant containers.
Identification—
Solution:
500 µg per mL.
Medium:
water.
Absorptivities at 257 nm, calculated on the dried basis, do not differ by more than 3.0%.
C:
A solution of it responds to the test for
Sulfate 
191
.
Specific rotation 781S:
between +56.0
and +59.0
.
Test solution:
50 mg per mL, in water.
pH 791:
between 5.0 and 6.5 in a solution (1 in 20).
Chloride 221—
A 200-mg portion shows no more chloride than corresponds to 0.4 mL of 0.02 N hydrochloric acid (0.14%).
Heavy metals—
Treat a solution of 1.0 g in 20 mL of dilute alcohol (1 in 2) with 5 mL of sodium hydroxide solution (1 in 20) and 5 drops of
sodium sulfide TS: the color developed is not darker than that of a blank determination performed simultaneously, containing 10 ppm of standard lead solution (see
Heavy Metals 231).
Ordinary impurities 466—
Test solution:
alcohol.
Standard solution:
alcohol.
Eluant:
a mixture of alcohol, glacial acetic acid, and water (10:3:1).
Visualization:
16.
Assay—
Dissolve about 150 mg of Pseudoephedrine Sulfate, accurately weighed, in 50 mL of glacial acetic acid. Titrate with 0.1 N perchloric acid VS, determining the endpoint potentiometrically. Perform a blank determination, and make any necessary correction. Each mL of 0.1 N perchloric acid is equivalent to 42.85 mg of (C10H15NO)2·H2SO4.
-[1-(methylamino)ethyl]-, [S-(R*,R*)]-, sulfate (2:1) (salt).