Packaging and storage
Preserve in tight containers.
It meets the requirements of the tests for Acetate 191
Heavy metals, Method I 231
Evaporate 5 mL in a porcelain dish on a steam bath to dryness. Warm the residue with 2 mL of 1 N acetic acid, and dilute with water to 50 mL. Dilute 20 mL of this solution with water to 25 mL: not more than 0.001% is found.
Readily oxidizable substances
To 20 mL in a glass-stoppered flask add 0.30 mL of 0.10 N potassium permanganate: the pink color is not changed to brown immediately, and the liquid does not become entirely brown or free from a pink tint in less than 30 seconds.
Limit of nonvolatile residue
Evaporate 20 mL in a tared porcelain dish on a steam bath, and dry it at 105
for 1 hour: the weight of the residue does not exceed 1.0 mg. Not more than 0.005% is found.
Limit of chloride
Add 5 drops of silver nitrate TS
to 10 mL of a solution (6 in 10): no opalescence is found.
Limit of sulfate
Add 5 drops of barium chloride TS
to 10 mL of a solution (6 in 10): no turbidity is produced.
Transfer 25.0 mL of Diluted Acetic Acid to a flask, and add 15 mL of carbon dioxidefree water. Add phenolphthalein TS
, and titrate with 1 N sodium hydroxide VS. Each mL of 1 N sodium hydroxide is equivalent to 60.05 mg of C2
: Feiwen Mao, M.S., Senior Scientific Associate
Expert Committee : (MDOOD05) Monograph Development-Ophthalmics Oncologics and Dermatologicals
USP29NF24 Page 3265
: Volume No. 27(4) Page 2788
Phone Number : 1-301-816-8320