U.S. PHARMACOPEIA

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1  For further detail regarding apparatus and procedures, reference may be made to the following publications of the American Society for Testing and Materials, 100 Barr Harbor Drive, West Conshohocken, PA19428-2959: “Standard Method of Test for Haze and Luminous Transmittance of Transparent Plastics,” ASTM Designation D-1003-61; “Tentative Method of Test for Luminous Reflectance, Transmittance, and Color of Materials,” ASTM E 308-66.
2  A suitable mortar and pestle is available (catalog No. H-17280) from Humboldt Manufacturing Co., 7300 West Agatite, Norridge, Chicago, IL 60656.
3  A suitable nuclear-grade resin mixture of the strong acid cation exchanger in the hydrogen form and the strong base anion exchanger in the hydroxide form, with a one-to-one cation to anion equivalence ratio, is available from the Millipore Corp., Bedford, MA 01730; Barnstead Co., 225 Rivermoor St., Boston, MA 02132; Illinois Water Treatment Co., 840 Cedar St., Rockford, IL 61105; and Vaponics, Inc., 200 Cordage Park, Plymouth, MA 02360.
A suitable in-line filter is available from the Millipore Corp.; Gelman Instrument Co., 600 S. Wagner Rd., Ann Arbor, MI 48106; and Schleicher and Schuell, Inc., 540 Washington St., Keene, NH 10003.
4  The multiple internal reflectance accessory and KRS-5 plate are available from several sources, including Beckman Instruments, Inc., 2500 Harbor Blvd., Fullerton, CA 92634, and from Perkin Elmer Corp., Main Ave., Norwalk, CT 06856.
5  A suitable laminate for sealing has as the container contact layer polyethylene of not less than 0.025 mm (0.001 inch) and a second layer of aluminum foil of not less than 0.018 mm (0.0007 inch), with additional layers of suitable backing materials. A suitable seal can be obtained also by using glass plates and a sealing wax consisting of 60% of refined amorphous wax and 40% of refined crystalline paraffin wax.
6  The multiple internal reflectance accessory and KRS-5 plate are available from several sources, including Beckman Instruments, Inc., 2500 Harbor Boulevard, Fullerton, CA 92634, and from Perkin Elmer Corporation, 761 Main Ave., Norwalk, CT 06859-01560.
7  It should be noted that there is no special exemption for patient med paks from the requirements of the Poison Prevention Packaging Act. Thus the patient med pak, if it does not meet child-resistant standards, shall be placed in an outer package that does comply, or the necessary consent of the purchaser or physician, to dispense in a container not intended to be child-resistant, shall be obtained.