U.S. PHARMACOPEIA

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USP Mafenide Acetate RS
Determine the water content titrimetrically at the time of use. Keep container tightly closed. Protect from light.

USP Mafenide Related Compound A RS
[4-formylbenzenesulfonamide] (C7H7NO3S 185.20) —Dry portion in vacuum at 60 for 4 hours before using. Keep container tightly closed. Protect from light.

USP Magaldrate RS
Do not dry before using. Keep container tightly closed, and store in a cool place.

USP Magnesium Salicylate RS
Dry portion at 105 for 4 hours before using. Keep container tightly closed.

USP Malathion RS
Do not dry. After opening ampul, transfer contents to a suitable container. Keep container tightly closed and protected from light. Store in a refrigerator.

USP Maleic Acid RS
Do not dry. Keep container tightly closed and protected from light.

USP Malic Acid RS
Do not dry before using. Keep container tightly closed and protected from light.

USP Maltitol RS
Do not dry before using. Keep container tightly closed.

USP Maltol RS.

USP Maltose RS—
Do not dry; determine the water content titrimetrically at the time of use for quantitative analyses. Keep container tightly closed.
Change to read:

USP Maltose Monohydrate RS
Do not dry. Keep container tightly closed.USP29

USP Mangafodipir Trisodium RS
[manganese(II) dipyridoxal diphosphate]— Do not dry. Hygroscopic. For quantitative applications, determine the water content titrimetrically at the time of use. After opening vial, store tightly closed in a desiccator. Store in a refrigerator.

USP Mangafodipir Related Compound A RS
[manganese(II) dipyridoxal monophosphate sodium salt]— Do not dry. Hygroscopic. After opening vial, store tightly closed in a desiccator. Store in a refrigerator.

USP Mangafodipir Related Compound B RS
[manganese(II) dipyridoxal diphosphate mono overalkylated sodium salt]— Do not dry. Hygroscopic. After opening vial, store tightly closed in a desiccator. Store in a refrigerator.

USP Mangafodipir Related Compound C RS
[manganese(II) dipyridoxal diphosphate sodium salt]— Do not dry. Hygroscopic. After opening vial, store tightly closed in a desiccator. Store in a freezer.

USP Mannitol RS
Do not dry before using. Keep container tightly closed.

USP Maprotiline Hydrochloride RS
Dry portion in vacuum at 80 to constant weight before using. Keep container tightly closed.

USP Maritime Pine Extract RS
Do not dry. Keep container tightly closed and protected from light.

USP Mazindol RS
Dry portion in vacuum at 60 for 2 hours before using. Keep container tightly closed. Store at a temperature not exceeding 25.

USP Mebendazole RS
Dry portion at 105 for 4 hours before using. Keep container tightly closed.

USP Mebrofenin RS
Do not dry. Keep container tightly closed.

USP Mecamylamine Hydrochloride RS
Dry portion at a pressure not exceeding 5 mm of mercury at 105 for 1 hour before using. Keep container tightly closed. Store in a cool, dry place.

USP Mecamylamine Related Compound A RS
[N,1,7,7-tetramethyl bicyclo [2.2.1] heptan-2-amine] (C11H21N 167.29).

USP Mechlorethamine Hydrochloride RS
Do not dry before using. This material is hygroscopic. Keep container tightly closed, protected from light.

USP Meclizine Hydrochloride RS
Do not dry; determine the water content titrimetrically at the time of use. Keep container tightly closed.

USP Meclocycline Sulfosalicylate RS
Do not dry; determine the water content titrimetrically at the time of use. Keep container tightly closed. Protect from light.

USP Meclofenamate Sodium RS
Do not dry; determine the water content titrimetrically at time of use. Keep container tightly closed. Protect from light.

USP Medroxyprogesterone Acetate RS
Do not dry. Keep container tightly closed. Protect from light.

USP Medroxyprogesterone Acetate Related Compound A RS
[4,5-dihydromedroxyprogesterone acetate] (C24H36O4 388.54) —Do not dry before using. Keep container tightly closed.

USP Mefenamic Acid RS
Do not dry. Keep container tightly closed. Protect from light.

USP Mefloquine Hydrochloride RS.

USP Mefloquine Related Compound A RS
[threo-mefloquine].

USP Megestrol Acetate RS
Do not dry; determine the water content titrimetrically at time of use. Keep container tightly closed. Protect from light.

USP Melengestrol Acetate RS.

USP Melengestrol Acetate Related Compound A RS
[16-methylene-17-hydroxy-4-pregnene-3,20-dione 17-acetate] —Do not dry. Keep container tightly closed. Protect from light.

USP Melengestrol Acetate Related Compound B RS
[17-hydroxy-6,16-dimethyleneprogna-4-ene-3,20-dione 17-acetate] —Do not dry. Keep container tightly closed. Protect from light.

USP Melphalan Hydrochloride RS
Do not dry before using. Keep container tightly closed and protected from light. Store in a refrigerator.

USP Menadione RS
[CautionAvoid contact; avoid exposure to light. ] Dry portion over silica gel for 4 hours before using. Keep container tightly closed. Protect from light.

USP Menotropins RS.

USP Menthol RS
Do not dry. This is the L-form of menthol. Keep container tightly closed. Protect from light.

USP Meperidine Hydrochloride RS
Dry portion in vacuum at a pressure between 20 and 40 mm of mercury at 80 for 4 hours before using. Keep container tightly closed. Protect from light.

USP Mephobarbital RS
Dry portion at 105 for 4 hours before using. Keep container tightly closed.

USP Mepivacaine Hydrochloride RS
Dry portion at 105 for 4 hours before using. Keep container tightly closed.

USP Meprednisone RS
Dry portion at 105 for 3 hours before using. Keep container tightly closed. Protect from light.

USP Meprobamate RS
Dry portion in vacuum at 60 for 3 hours before using. Keep container tightly closed.

USP Meradimate RS.

USP 3-Mercapto-2-methylpropanoic Acid 1,2-Diphenylethylamine Salt RS
(C4H7O2S·C14H16N 317.45) —Do not dry before using. Keep container tightly closed.

USP Mercaptopurine RS
Do not dry; determine the water content titrimetrically at time of use. Keep container tightly closed.

USP Meropenem RS—
Do not dry. For quantitative applications, determine the water content titrimetrically at the time of use. Keep container tightly closed. Store in a refrigerator.

USP Mesalamine RS
Dry portion in vacuum at 105 for 3 hours before using. Keep container tightly closed and protected from light.

USP Mesoridazine Besylate RS—
Do not dry. Keep container tightly closed. Protect from light.

USP Mestranol RS—
Do not dry. Keep container tightly closed. Protect from light.

USP Metaproterenol Sulfate RS
Dry portion at 105 for 1 hour before using. Keep container tightly closed. Protect from light.

USP Metaraminol Bitartrate RS
Dry portion at 105 for 2 hours before using. Keep container tightly closed.

USP Metformin Hydrochloride RS—
Do not dry. Keep container tightly closed. Store in a refrigerator. Keep away from alkali.

USP Metformin Related Compound A RS [1-cyanoguanidine]—
Do not dry. Keep container tightly closed. Store in a refrigerator. Keep away from alkali.

USP Methacrylic Acid Copolymer, Type A RS
Dry portion at 110 for 6 hours before using. Keep container tightly closed.

USP Methacrylic Acid Copolymer, Type B RS
Dry portion at 110 for 6 hours before using. Keep container tightly closed.

USP Methacrylic Acid Copolymer, Type C RS
Dry portion at 110 for 6 hours before using. Keep container tightly closed.

USP Methacycline Hydrochloride RS
Do not dry. Keep container tightly closed. Protect from light. Store in a freezer.

USP Methadone Hydrochloride RS
Do not dry. Keep container tightly closed. Protect from light.

USP Methamphetamine Hydrochloride RS
Dry portion at 105 for 2 hours before using. Keep container tightly closed. Protect from light.

USP Methazolamide RS
Dry portion at 105 for 2 hours before using. Keep container tightly closed. Protect from light.

USP Methdilazine Hydrochloride RS
Dry portion in vacuum at 65 for 16 hours before using. Keep container tightly closed.

USP Methenamine RS—
Do not dry. Keep container tightly closed.

USP Methenamine Hippurate RS
Dry portion in vacuum at 60 for 1 hour before using. Keep container tightly closed.

USP Methenamine Mandelate RS
Dry portion over silica gel for 18 hours before using. Keep container tightly closed.

USP Methicillin Sodium RS
Do not dry. Determine the water content titrimetrically at the time of use. Keep container tightly closed. Protect from light. Store in a cold place.

USP Methimazole RS
Dry portion at 105 for 2 hours before using. Keep container tightly closed. Protect from light and store in a freezer.
Change to read:

USP L-Methionine RS
Do not dry.USP29 Keep container tightly closed.

USP Methocarbamol RS
Dry portion at 60 for 2 hours before using. Keep container tightly closed.

USP Methohexital RS
Do not dry. Keep container tightly closed.

USP Methotrexate RS
This material is hygroscopic. Do not dry; determine the water content titrimetrically at time of use. Keep container tightly closed. Protect from light. Store in a refrigerator.

USP Methotrimeprazine RS
Dry portion at 100 for 3 hours before using. Keep container tightly closed. Protect from light.

USP Methoxsalen RS
Do not dry; determine the water content titrimetrically at time of use. Keep container tightly closed. Protect from light.

USP Methoxyflurane RS
Keep container tightly closed and protected from light.

USP 3-Methoxytyrosine RS—
(NAME CHANGE) See USP Levodopa Related Compound B RS.
Add the following:

USP Methscopolamine Bromide RS—
Dry portion at 105 for 3 hours before using.USP29

USP Methsuximide RS
Dry portion over phosphorus pentoxide for 16 hours before using. Keep container tightly closed.

USP Methyclothiazide RS
Dry portion at 105 for 4 hours before using. Keep container tightly closed.

USP Methyclothiazide Related Compound A RS
[4-amino-6-chloro-N3-methyl-m-benzenedisulfonamide] (C7H10ClN3O4S2 299.76) —Dry portion over silica gel for 4 hours before using. Keep container tightly closed and protected from light.

USP Methyl Caprate RS
Do not dry before using. After opening ampul, store in a tightly closed container, protected from light.

USP Methyl Caproate RS
Do not dry before using. After opening ampul, store in a tightly closed container, protected from light.

USP Methyl Caprylate RS
Do not dry before using. After opening ampul, store in a tightly closed container, protected from light. Store in a freezer.

USP Methyl Laurate RS
Do not dry before using. After opening ampul, store in a tightly closed container, protected from light.

USP Methyl Linoleate RS
Store in a freezer. Do not dry before using. After opening ampul, discard the unused portion.

USP Methyl Linolenate RS
Store in a freezer. Do not dry before using. After opening ampul, discard the unused portion.

USP Methyl 5-Methyl-3-isoxazolecarboxylate RS
Dry portion over silica gel for 4 hours before using. Keep container tightly closed and protected from light.

USP Methyl Myristate RS
Do not dry before using. After opening ampul, store in a tightly sealed container, protected from light.

USP Methyl Oleate RS
Store in a freezer. Do not dry before using. After opening ampul, store it in a tightly closed container under an inert gas, protected from light.

USP Methyl Palmitate RS
Do not dry before using. Keep container tightly closed. Store in a refrigerator.

USP Methyl Palmitoleate RS
Store in a freezer. Do not dry before using. After opening ampul, store it in a tightly closed container under an inert gas, protected from light.

USP Methyl Stearate RS
Do not dry before using. Keep container tightly closed. Store in a refrigerator.

USP Methyldopa RS
Do not dry; determine the water content titrimetrically at time of use. Keep container tightly closed. Protect from light.

USP Methyldopa-Glucose Reaction Product RS.

USP Methyldopate Hydrochloride RS
Dry portion at a pressure not exceeding 5 mm of mercury at 100 for 2 hours before using. Keep container tightly closed.

USP Methylene Blue RS
Dry portion at a pressure not exceeding 5 mm of mercury at 75 for 4 hours before using. Keep container tightly closed.

USP Methylergonovine Maleate RS
Dry portion in vacuum at 80 to constant weight before using. Keep container tightly closed. Protect from light. Store in a refrigerator.

USP 3-O-Methylmethyldopa RS
(C11H15NO4 225.25) —Do not dry. This is the monohydrate form of 3-O-methylmethyldopa. Keep container tightly closed. Protect from light.

USP Methylparaben RS
Dry portion over silica gel for 5 hours before using. Keep container tightly closed.

USP Methylphenidate Hydrochloride RS
Dry portion in vacuum at 60 for 4 hours before using. Keep container tightly closed.

USP Methylphenidate Hydrochloride Erythro Isomer Solution RS
This solution contains 0.5 mL of methylphenidate hydrochloride erythro isomer per mL in methanol. Store in a refrigerator.

USP Methylphenidate Related Compound A RS
[-phenyl-2-piperidineacetic acid hydrochloride] (C13H17NO2·HCl 255.75) —Do not dry before using. Keep container tightly closed.

USP Methylprednisolone RS
Dry portion at 105 for 3 hours before using. Keep container tightly closed. Protect from light.

USP Methylprednisolone Acetate RS
Do not dry. Keep container tightly closed. Protect from light. Store in a freezer.

USP Methylprednisolone Hemisuccinate RS—
Do not dry. Keep container tightly closed. Protect from light. Store in a cool place.

USP Methyltestosterone RS
Dry portion at 105 for 4 hours before using. Keep container tightly closed. Protect from light.

USP Methysergide Maleate RS
Dry portion in vacuum at 120 for 2 hours before using. Keep container tightly closed. Protect from light.

USP Metoclopramide Hydrochloride RS
Do not dry; determine the water content titrimetrically at time of use for quantitative analyses. Keep container tightly closed. Protect from light.

USP Metolazone RS
Dry portion at 105 for 2 hours before using. Keep container tightly closed. Protect from light.

USP Metoprolol Fumarate RS
Dry portion in vacuum at 60 for 4 hours before using. Keep container tightly closed and protected from light.

USP Metoprolol Related Compound A RS
[(±)1-ethylamino)-3-[4-(2-methoxyethyl)phenoxy]-propan-2-ol] (C14H23NO3 253.34) —Do not dry. Keep container tightly closed. Protect from light. Store in a freezer.

USP Metoprolol Related Compound B RS
[(±)1-chloro-2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]-propane] (C12H17ClO3 244.71) —Do not dry. Keep container tightly closed. Protect from light. Store in a freezer.

USP Metoprolol Related Compound C RS
[(±)4-[2-hydroxy-3-(1-methylethyl)aminopropoxy]benzaldehyde] (C13H19NO3 237.29) —Do not dry. Keep container tightly closed. Protect from light. Store in a freezer.

USP Metoprolol Related Compound D RS
[(±) N,N-bis[2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl](1-methylethyl)amine] (C27H41NO6 475.62) —Do not dry. Keep container tightly closed. Protect from light. Store in a freezer.

USP Metoprolol Succinate RS
Do not dry. Keep container tightly closed. Protect from light.

USP Metoprolol Tartrate RS
Keep container tightly closed. Protect from light.

USP Metrifonate RS [trichlorfon]—
Do not dry. Keep container tightly closed, protected from light, and store in a refrigerator.

USP Metronidazole RS
Dry portion at 105 for 2 hours before using. Keep container tightly closed. Protect from light.

USP Metronidazole Benzoate RS—
Dry at 80 for 3 hours.

USP Metyrapone RS
Dry portion in vacuum at room temperature for 6 hours before using. Keep container tightly closed. Protect from light. Store in a cool, dry place.

USP Metyrosine RS
Dry portion at a pressure not exceeding 5 mm of mercury at 100 for 2 hours before using. Keep container tightly closed.

USP Mexiletine Hydrochloride RS
Dry portion at 105 for 2 hours before using. Keep container tightly closed.

USP Mezlocillin Sodium RS
Do not dry. For quantitative applications, determine the water content titrimetrically at the time of use. Keep container tightly closed, and store in a cool, dry place. This material is hygroscopic.

USP Mibolerone RS.

USP Miconazole RS
Dry portion in vacuum at 60 for 4 hours before using. Keep container tightly closed. Protect from light.

USP Miconazole Nitrate RS
Dry portion at 105 for 2 hours before using. Keep container tightly closed. Protect from light.

USP Powdered Milk Thistle Extract RS
Dry portion at 105 for 2 hours before using.

USP Milrinone RS—
Do not dry. For quantitative applications, determine the water content titrimetrically at the time of use. This material is hygroscopic. Keep container tightly closed.

USP Milrinone Related Compound A RS
[1,6-dihydro-2-methyl-6-oxo-(3,4¢-bipyridine)-5-carboxamide] (C12H11N3O2 229.23) —Do not dry. This material is hygroscopic. Keep container tightly closed.

USP Minocycline Hydrochloride RS
Do not dry before using. Keep container tightly closed. Protect from light. Store in a cold place.

USP Minoxidil RS
Do not dry before using. Keep container tightly closed.

USP Mirtazapine RS
—Do not dry; determine the water content titrimetrically at the time of use. Keep container tightly closed. Protect from light.

USP Mitomycin RS
Do not dry before using. Keep container tightly closed. Protect from light. Store in a cold dry place.

USP Mitotane RS
Dry portion in vacuum at 60 for 2 hours before using. Keep container tightly closed. Protect from light.

USP Mitoxantrone Hydrochloride RS
Do not dry; determine the water content titrimetrically at the time of use. Keep container tightly closed. This material is hygroscopic.

USP Mitoxantrone System Suitability Mixture RS
[9, 10-anthracenedione, 8-amino-1,4-dihydroxy-5[[2-[(2-hydroxyethyl)amino]ethyl]amino]-, hydrochloride] (C18H19N3O5·HCl 393.83) —Do not dry. Keep container tightly closed.

USP Molindone Hydrochloride RS
Dry portion at 105 to constant weight before using. Keep container tightly closed. Protect from light.

USP Mometasone Furoate RS
Dry portion at 105 for 3 hours before using. Keep container tightly closed.

USP Monensin Sodium RS.

USP Monobenzone RS
Dry portion at 105 for 3 hours before using. Keep container tightly closed. Protect from light. Avoid exposure to temperatures above 30.

USP Monoglycerides RS
Do not dry before using. Keep container tightly closed and protected from light.

USP Monostearyl Maleate RS
Do not dry. Keep container tightly closed.

USP Morantel Tartrate RS
Do not dry. Keep container tightly closed. Protect from light. After opening, store in a desiccator.

USP Moricizine Hydrochloride RS
Do not dry. For quantitative applications, determine the water content titrimetrically. Keep container tightly closed.

USP Morphine Sulfate RS
This is the pentahydrate form. Do not dry before using, except as instructed for compliance with official standards. Determine the water content titrimetrically at time of use. Keep container tightly closed. Protect from light.

USP Mupirocin RS
Do not dry before using. Keep container tightly closed, and store in a freezer.

USP Mupirocin Lithium RS
Do not dry before using. Keep container tightly closed, and store in a freezer.